.systems-disease-page {
  --sd-dark: #061016;
  --sd-ink: #092b37;
  --sd-teal: #0a7b81;
  --sd-cyan: #25c8c0;
  --sd-paper: #f8f7f4;
  color: #0b2732;
  font-family: "Manrope", "Plus Jakarta Sans", Arial, sans-serif;
}

.systems-disease-page h1,
.systems-disease-page h2,
.systems-disease-page h3,
.systems-disease-page p {
  margin: 0;
}

.sd-nav {
  align-items: stretch;
  background: #040b10;
  display: grid;
  grid-template-columns: 310px minmax(0, 1fr);
  min-height: 130px;
}

.sd-brand {
  align-content: center;
  border-right: 1px solid rgba(255, 255, 255, 0.18);
  display: grid;
  padding-left: 28px;
  text-decoration: none;
}

.sd-brand img {
  filter: brightness(0) invert(1);
  height: 76px;
  object-fit: contain;
  object-position: left center;
  width: 270px;
}

.sd-brand span {
  color: rgba(255, 255, 255, 0.83);
  font-size: 13px;
  font-weight: 700;
  letter-spacing: 0.11em;
  margin-left: 70px;
  margin-top: -12px;
  text-transform: uppercase;
}

.sd-menu {
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
}

.sd-menu a {
  border-right: 1px solid rgba(255, 255, 255, 0.18);
  color: #fff;
  display: flex;
  flex-direction: column;
  gap: 10px;
  justify-content: center;
  padding: 0 14px;
  text-align: center;
  text-decoration: none;
}

.sd-menu strong {
  color: #fff;
  font-size: 13px;
  font-weight: 900;
  line-height: 1.32;
  text-transform: uppercase;
}

.sd-menu a.active strong {
  color: #28d8d0;
}

.sd-menu strong::after {
  content: "⌄";
  font-size: 12px;
  margin-left: 5px;
}

.sd-menu span {
  color: rgba(255, 255, 255, 0.82);
  font-size: 11px;
  font-weight: 700;
  line-height: 1.5;
}

.sd-hero {
  background:
    radial-gradient(circle at 72% 38%, rgba(24, 180, 180, 0.19), transparent 31%),
    linear-gradient(90deg, #071017 0%, #0a222b 54%, #051016 100%);
  display: grid;
  grid-template-columns: 52% 48%;
  min-height: 520px;
  overflow: hidden;
}

.sd-hero-copy {
  display: flex;
  flex-direction: column;
  justify-content: center;
  padding: 46px 28px 36px 72px;
}

.sd-hero-copy h1 {
  color: #f7f0e8;
  font-family: "Playfair Display", Georgia, serif;
  font-size: clamp(38px, 3.45vw, 49px);
  font-weight: 500;
  line-height: 1.14;
}

.sd-hero-copy h1 span {
  color: #35d0c5;
}

.sd-hero-copy p {
  color: rgba(255, 255, 255, 0.92);
  font-size: 20px;
  font-weight: 500;
  line-height: 1.55;
  margin-top: 0;
  max-width: 640px;
}

.sd-hero-rule {
  background: #22c8c4;
  height: 3px;
  margin: 26px 0 22px;
  width: 92px;
}

.sd-hero-pillars {
  display: grid;
  grid-template-columns: repeat(4, minmax(0, 1fr));
  margin-top: 34px;
  max-width: 650px;
}

.sd-hero-pillars div {
  border-left: 1px solid rgba(255, 255, 255, 0.18);
  display: grid;
  gap: 9px;
  justify-items: center;
  text-align: center;
}

.sd-hero-pillars div:first-child {
  border-left: 0;
}

.sd-hero-pillars i {
  color: #24c8c0;
  font-size: 48px;
}

.sd-hero-pillars strong {
  color: #fff;
  font-size: 18px;
  font-weight: 900;
  letter-spacing: 0.05em;
  text-transform: uppercase;
}

.sd-hero-art {
  align-items: center;
  display: flex;
  justify-content: center;
  min-height: 520px;
  position: relative;
}

.sd-hero-art img {
  display: block;
  max-height: 520px;
  max-width: 760px;
  object-fit: contain;
  opacity: 0.98;
  width: 100%;
}

.sd-orbit {
  align-items: center;
  border: 1px solid rgba(36, 200, 192, 0.7);
  border-radius: 50%;
  color: #24c8c0;
  display: inline-flex;
  font-size: 34px;
  height: 82px;
  justify-content: center;
  position: absolute;
  width: 82px;
}

.sd-orbit.orbit-a {
  left: 5%;
  top: 12%;
}

.sd-orbit.orbit-b {
  right: 8%;
  top: 12%;
}

.sd-orbit.orbit-c {
  left: 2%;
  top: 44%;
}

.sd-orbit.orbit-d {
  right: 4%;
  top: 46%;
}

.sd-paper {
  background: var(--sd-paper);
  padding: 30px 14px 22px;
}

.sd-equation-panel {
  margin: 0 auto 22px;
  max-width: 1240px;
}

.sd-equation-heading {
  text-align: center;
}

.sd-equation-heading h2 {
  color: #132b35;
  font-family: "Playfair Display", Georgia, serif;
  font-size: 29px;
  font-weight: 900;
  letter-spacing: 0.12em;
  line-height: 1.2;
  text-transform: uppercase;
}

.sd-equation-heading p {
  color: #0a7b81;
  font-family: "Playfair Display", Georgia, serif;
  font-size: 24px;
  letter-spacing: 0.08em;
  line-height: 1.25;
  margin-top: 5px;
  text-transform: uppercase;
}

.sd-equation-heading::after {
  background: #1fb7b1;
  content: "";
  display: block;
  height: 2px;
  margin: 14px auto 22px;
  width: 60px;
}

.sd-equation-card {
  background: rgba(255, 255, 255, 0.84);
  border: 1px solid rgba(8, 45, 54, 0.26);
  border-radius: 10px;
  box-shadow: 0 12px 28px rgba(9, 38, 46, 0.07);
  display: grid;
  grid-template-columns: 195px minmax(0, 1fr);
  min-height: 348px;
  padding: 28px 38px 26px 30px;
}

.sd-equation-master {
  align-items: center;
  border-right: 2px solid rgba(9, 94, 105, 0.34);
  display: flex;
  flex-direction: column;
  justify-content: center;
  text-align: center;
  text-transform: uppercase;
}

.sd-equation-master h3 {
  color: #0a4656;
  font-size: 24px;
  font-weight: 900;
  line-height: 1.25;
}

.sd-equation-master span {
  align-items: center;
  border: 1px solid rgba(10, 123, 129, 0.35);
  border-radius: 50%;
  color: #0a7b81;
  display: inline-flex;
  font-family: Georgia, serif;
  font-size: 92px;
  height: 145px;
  justify-content: center;
  margin-top: 30px;
  outline: 1px solid rgba(10, 123, 129, 0.28);
  outline-offset: 8px;
  width: 145px;
}

.sd-equation-main {
  display: grid;
  grid-template-rows: auto 1fr auto;
  min-width: 0;
  padding-left: 32px;
}

.sd-formula {
  align-items: center;
  display: grid;
  gap: 12px;
  grid-template-columns: minmax(0, 1.24fr) auto minmax(0, 1.14fr) auto minmax(0, 0.82fr) auto minmax(0, 0.8fr) auto minmax(0, 1.14fr);
  min-width: 0;
  padding-top: 8px;
  text-align: center;
}

.sd-formula strong {
  color: #1b2f37;
  font-family: "Playfair Display", Georgia, serif;
  font-size: 17px;
  font-weight: 900;
  min-width: 0;
  white-space: nowrap;
}

.sd-formula em {
  color: #1b2f37;
  font-style: normal;
  font-size: 19px;
  font-weight: 900;
}

.sd-formula-items {
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
  text-align: center;
}

.sd-formula-items div {
  align-content: start;
  border-left: 1px solid rgba(8, 45, 54, 0.13);
  display: grid;
  justify-items: center;
  padding: 40px 14px 0;
}

.sd-formula-items div:first-child {
  border-left: 0;
}

.sd-formula-items i {
  align-items: center;
  border: 1px solid rgba(8, 45, 54, 0.22);
  border-radius: 50%;
  color: #0a6570;
  display: inline-flex;
  font-size: 38px;
  height: 76px;
  justify-content: center;
  margin-bottom: 18px;
  width: 76px;
}

.sd-formula-items p {
  color: #102a33;
  font-size: 14px;
  font-weight: 800;
  line-height: 1.45;
  max-width: 150px;
}

.sd-equation-note {
  border: 1px solid #0b7180;
  border-radius: 5px;
  color: #18323a;
  font-size: 15px;
  font-weight: 800;
  padding: 13px 18px;
  text-align: center;
}

.sd-panel {
  background: rgba(255, 255, 255, 0.82);
  border: 1px solid rgba(8, 45, 54, 0.24);
  border-radius: 14px;
  box-shadow: 0 10px 24px rgba(9, 38, 46, 0.07);
  margin: 0 auto 24px;
  max-width: 1240px;
}

.sd-panel.overlap {
  margin-top: 0;
  position: relative;
  z-index: 2;
}

.sd-title {
  padding-top: 25px;
  text-align: center;
}

.sd-title h2 {
  color: #132b35;
  font-family: "Playfair Display", Georgia, serif;
  font-size: 26px;
  font-weight: 900;
  letter-spacing: 0.12em;
  line-height: 1.25;
  text-transform: uppercase;
}

.sd-title p {
  color: #173541;
  font-size: 16px;
  font-weight: 600;
  margin-top: 4px;
}

.sd-title::after {
  background: #1fb7b1;
  content: "";
  display: block;
  height: 2px;
  margin: 13px auto 0;
  width: 58px;
}

.sd-load-grid {
  display: grid;
  grid-template-columns: repeat(7, 1fr);
  padding: 26px 22px 38px;
  text-align: center;
}

.sd-load-grid div {
  border-left: 1px solid rgba(8, 45, 54, 0.14);
  padding: 0 16px;
}

.sd-load-grid div:first-child {
  border-left: 0;
}

.sd-load-grid i {
  align-items: center;
  border: 1px solid rgba(9, 126, 132, 0.56);
  border-radius: 50%;
  color: #0a7b81;
  display: inline-flex;
  font-size: 42px;
  height: 82px;
  justify-content: center;
  width: 82px;
}

.sd-load-grid strong {
  color: #0a4656;
  display: block;
  font-size: 15px;
  font-weight: 900;
  margin-top: 18px;
  text-transform: uppercase;
}

.sd-load-grid p {
  color: #132d38;
  font-size: 12px;
  font-weight: 700;
  line-height: 1.45;
  margin-top: 10px;
}

.sd-hierarchy {
  padding: 0 28px 32px;
}

.sd-hierarchy-layout {
  display: grid;
  gap: 24px;
  grid-template-columns: 150px minmax(0, 1fr) 390px;
  margin-top: 24px;
}

.sd-categories {
  display: grid;
  gap: 7px;
  grid-template-rows: 119px 186px 186px 148px 112px;
}

.sd-categories span {
  align-items: center;
  background: #dcecef;
  border-radius: 4px;
  color: #0b3b4a;
  display: flex;
  font-size: 17px;
  font-weight: 900;
  justify-content: center;
  line-height: 1.3;
  text-align: center;
  text-transform: uppercase;
}

.sd-layer-list {
  border: 1px solid rgba(8, 45, 54, 0.12);
  border-radius: 4px;
  overflow: hidden;
}

.sd-layer {
  align-items: center;
  background: rgba(255, 255, 255, 0.62);
  border-bottom: 1px solid rgba(8, 45, 54, 0.13);
  display: grid;
  gap: 14px;
  grid-template-columns: 36px 46px 245px minmax(0, 1fr);
  min-height: 62px;
  padding: 7px 14px;
}

.sd-layer:last-child {
  border-bottom: 0;
}

.sd-layer .num {
  align-items: center;
  background: #064b5a;
  border-radius: 50%;
  color: #fff;
  display: inline-flex;
  font-size: 14px;
  font-weight: 900;
  height: 32px;
  justify-content: center;
  width: 32px;
}

.sd-layer i {
  color: #0a7b81;
  font-size: 28px;
  text-align: center;
}

.sd-layer strong {
  color: #0b3b4a;
  font-size: 14px;
  font-weight: 900;
  line-height: 1.25;
  text-transform: uppercase;
}

.sd-layer p {
  color: #172f38;
  font-size: 13px;
  font-weight: 700;
  line-height: 1.28;
}

.sd-quote {
  background: linear-gradient(145deg, #0b7477, #052933);
  border-radius: 7px;
  color: #fff;
  padding: 50px 42px 32px;
  position: relative;
}

.sd-quote blockquote {
  color: #fff;
  font-family: "Playfair Display", Georgia, serif;
  font-size: 27px;
  line-height: 1.45;
  margin: 0 0 34px;
}

.sd-quote blockquote::before {
  color: #57e0d8;
  content: "“";
  font-size: 58px;
  line-height: 0;
  margin-right: 10px;
  vertical-align: -18px;
}

.sd-quote div {
  border-top: 1px solid rgba(255, 255, 255, 0.5);
  display: grid;
  gap: 22px;
  grid-template-columns: 70px 1fr;
  padding: 28px 0 0;
}

.sd-quote div + div {
  border-top: 0;
}

.sd-quote i {
  align-items: center;
  border: 1px solid rgba(255, 255, 255, 0.45);
  border-radius: 50%;
  color: #fff;
  display: inline-flex;
  font-size: 38px;
  height: 66px;
  justify-content: center;
  width: 66px;
}

.sd-quote p {
  color: rgba(255, 255, 255, 0.92);
  font-size: 20px;
  line-height: 1.45;
}

.sd-loop {
  margin: 26px auto 24px;
  max-width: 1240px;
}

.sd-loop-grid {
  display: grid;
  gap: 18px;
  grid-template-columns: minmax(0, 1fr) 410px;
  margin-top: 26px;
}

.sd-loop-card {
  background: rgba(255, 255, 255, 0.76);
  border: 1px solid rgba(8, 45, 54, 0.22);
  border-radius: 10px;
  display: grid;
  grid-template-columns: 0.9fr 1.1fr;
  padding: 28px;
}

.sd-loop-copy h3,
.sd-loop-matter h3 {
  color: #0d3f4f;
  font-size: 15px;
  font-weight: 900;
  letter-spacing: 0.08em;
  text-transform: uppercase;
}

.sd-loop-copy p {
  color: #17313b;
  font-size: 14px;
  font-weight: 700;
  line-height: 1.65;
  margin-top: 18px;
}

.sd-cycle {
  min-height: 270px;
  position: relative;
}

.sd-cycle-image {
  align-items: center;
  display: flex;
  justify-content: center;
  min-height: 270px;
}

.sd-cycle-image img {
  display: block;
  height: auto;
  max-height: 310px;
  max-width: 100%;
  object-fit: contain;
  width: min(100%, 480px);
}

.sd-cycle strong,
.sd-cycle span {
  color: #0b3b4a;
  font-size: 12px;
  font-weight: 800;
  position: absolute;
  text-align: center;
}

.sd-cycle strong {
  left: 50%;
  line-height: 1.25;
  text-transform: uppercase;
  top: 44%;
  transform: translate(-50%, -50%);
}

.sd-cycle i {
  color: #0a7b81;
  display: block;
  font-size: 32px;
}

.sd-cycle span:nth-child(1) { left: 42%; top: 0; }
.sd-cycle span:nth-child(2) { right: 4%; top: 30%; }
.sd-cycle span:nth-child(4) { right: 12%; bottom: 8%; }
.sd-cycle span:nth-child(5) { left: 28%; bottom: 3%; }
.sd-cycle span:nth-child(6) { left: 2%; top: 34%; }

.sd-loop-matter {
  background: linear-gradient(145deg, #063c48, #041d27);
  border-radius: 9px;
  color: #fff;
  display: flex;
  flex-direction: column;
  padding: 34px 30px;
}

.sd-loop-matter h3 {
  color: #fff;
  margin-bottom: 24px;
}

.sd-loop-matter p {
  align-items: flex-start;
  color: rgba(255, 255, 255, 0.92);
  display: flex;
  font-size: 16px;
  gap: 12px;
  line-height: 1.45;
  margin-top: 20px;
}

.sd-loop-matter i {
  color: #fff;
  flex: 0 0 auto;
}

.sd-loop-cta {
  align-items: center;
  background: linear-gradient(180deg, #f0c66f, #dfa84a);
  border: 1px solid rgba(255, 226, 150, 0.9);
  border-radius: 5px;
  box-shadow: 0 10px 20px rgba(0, 0, 0, 0.18);
  color: #15252a;
  display: inline-flex;
  font-size: 14px;
  font-weight: 900;
  gap: 12px;
  justify-content: center;
  margin-top: 34px;
  min-height: 52px;
  padding: 0 22px;
  text-decoration: none;
  text-transform: uppercase;
  width: min(100%, 355px);
}

.sd-loop-cta i {
  border: 1px solid rgba(21, 37, 42, 0.38);
  border-radius: 4px;
  color: #15252a;
  font-size: 17px;
  height: 24px;
  line-height: 22px;
  text-align: center;
  width: 24px;
}

.sd-loop-cta:hover {
  color: #15252a;
  transform: translateY(-1px);
}

.sd-bottom-band {
  align-items: center;
  background: linear-gradient(90deg, #05343f, #031922);
  border-radius: 8px;
  color: #fff;
  display: grid;
  gap: 30px;
  grid-template-columns: 1fr 560px;
  margin: 0 auto;
  max-width: 1240px;
  padding: 22px 40px;
}

.sd-bottom-band blockquote {
  color: #fff;
  font-family: "Playfair Display", Georgia, serif;
  font-size: 17px;
  line-height: 1.55;
  margin: 0;
  padding-left: 36px;
  position: relative;
}

.sd-bottom-band blockquote::before {
  color: #fff;
  content: "“";
  font-size: 48px;
  left: 0;
  line-height: 1;
  position: absolute;
  top: -8px;
}

.sd-band-steps {
  border-left: 1px solid rgba(255, 255, 255, 0.28);
  display: grid;
  grid-template-columns: repeat(4, 1fr);
  text-align: center;
}

.sd-band-steps i {
  color: #fff;
  display: block;
  font-size: 42px;
}

.sd-band-steps strong {
  color: #6fe5df;
  display: block;
  font-size: 12px;
  font-weight: 900;
  line-height: 1.15;
  margin-top: 8px;
  text-transform: uppercase;
}

.sd-values-strip {
  background: #fbfaf5;
  border: 1px solid rgba(8, 45, 54, 0.12);
  border-radius: 8px;
  box-shadow: 0 10px 26px rgba(8, 45, 54, 0.08);
  display: grid;
  grid-template-columns: repeat(5, minmax(0, 1fr));
  margin: 36px auto 48px;
  max-width: 1660px;
  padding: 32px 0;
  width: calc(100% - 120px);
  position: relative;
  z-index: 2;
}

.sd-values-strip article {
  border-left: 1px solid rgba(8, 45, 54, 0.16);
  display: flex;
  flex-direction: column;
  justify-content: center;
  min-height: 205px;
  padding: 0 30px;
  text-align: center;
}

.sd-values-strip article:first-child {
  border-left: 0;
}

.sd-values-strip i {
  color: #16898d;
  display: block;
  font-size: 50px;
  margin-bottom: 24px;
}

.sd-values-strip strong {
  color: #263a42;
  display: block;
  font-size: 17px;
  font-weight: 900;
  margin-bottom: 14px;
}

.sd-values-strip p {
  color: #40555d;
  font-size: 13px;
  font-weight: 700;
  line-height: 1.45;
}

.sd-footer {
  background:
    radial-gradient(circle at 72% 15%, rgba(17, 163, 158, 0.12), transparent 32%),
    linear-gradient(180deg, #05343f 0%, #031923 100%);
  color: #eef8f7;
  padding: 30px 64px 18px;
}

.sd-footer-main {
  display: grid;
  gap: 34px;
  grid-template-columns: 1.35fr 0.86fr 0.98fr 0.72fr 1.08fr;
  margin: 0 auto;
  max-width: 1660px;
}

.sd-footer-brand,
.sd-footer-col,
.sd-footer-connect {
  border-left: 1px solid rgba(255, 255, 255, 0.1);
  min-width: 0;
  padding-left: 34px;
}

.sd-footer-brand {
  border-left: 0;
  padding-left: 0;
}

.sd-footer-brand img {
  filter: brightness(0) invert(1) contrast(1.12);
  height: 76px;
  object-fit: contain;
  object-position: left center;
  width: 305px;
}

.sd-footer-brand p {
  color: rgba(255, 255, 255, 0.78);
  font-size: 14px;
  font-weight: 700;
  line-height: 1.65;
  margin-top: 20px;
  max-width: 310px;
}

.sd-footer h3 {
  color: #f7fbfa;
  font-size: 15px;
  font-weight: 900;
  letter-spacing: 0.04em;
  margin-bottom: 16px;
  text-transform: uppercase;
}

.sd-footer-col {
  display: flex;
  flex-direction: column;
}

.sd-footer-col a {
  color: rgba(255, 255, 255, 0.78);
  font-size: 13px;
  font-weight: 700;
  line-height: 1.45;
  margin-top: 8px;
  text-decoration: none;
}

.sd-footer-col a:hover {
  color: #2edbd4;
}

.sd-socials {
  display: flex;
  gap: 12px;
  margin: 6px 0 28px;
}

.sd-socials a {
  align-items: center;
  border: 1px solid rgba(255, 255, 255, 0.35);
  border-radius: 50%;
  color: #fff;
  display: inline-flex;
  font-size: 22px;
  height: 42px;
  justify-content: center;
  text-decoration: none;
  width: 42px;
}

.sd-socials a:hover {
  border-color: #2edbd4;
  color: #2edbd4;
}

.sd-footer-cta {
  align-items: center;
  background: linear-gradient(90deg, #118f8d, #22c8c0);
  border-radius: 7px;
  box-shadow: 0 10px 22px rgba(16, 169, 164, 0.2);
  color: #fff;
  display: inline-flex;
  font-size: 16px;
  font-weight: 900;
  gap: 12px;
  justify-content: center;
  min-height: 64px;
  padding: 0 24px;
  text-decoration: none;
  text-transform: uppercase;
  width: 100%;
}

.sd-footer-cta i {
  border: 1px solid rgba(255, 255, 255, 0.5);
  border-radius: 4px;
  font-size: 21px;
  height: 30px;
  line-height: 28px;
  text-align: center;
  width: 30px;
}

.sd-footer-cta:hover {
  color: #fff;
  transform: translateY(-1px);
}

.sd-footer-bottom {
  align-items: center;
  border-top: 1px solid rgba(255, 255, 255, 0.12);
  display: flex;
  font-size: 14px;
  font-weight: 700;
  justify-content: space-between;
  margin: 28px auto 0;
  max-width: 1660px;
  padding-top: 18px;
}

.sd-footer-bottom span {
  color: rgba(255, 255, 255, 0.82);
}

.sd-footer-bottom strong {
  color: #2edbd4;
  font-weight: 900;
}

@media (max-width: 720px) {
  .sd-nav,
  .sd-hero,
  .sd-hierarchy-layout,
  .sd-loop-grid,
  .sd-bottom-band {
    grid-template-columns: 1fr;
  }

  .sd-menu,
  .sd-load-grid,
  .sd-band-steps {
    grid-template-columns: repeat(2, 1fr);
  }

  .sd-panel.overlap {
    margin-top: 0;
  }

  .sd-hero-art img {
    max-height: 360px;
  }
}

@media (max-width: 720px) {
  .sd-menu {
    display: none;
  }

  .sd-nav {
    min-height: 100px;
  }

  .sd-brand {
    padding-left: 18px;
  }

  .sd-brand img {
    height: 54px;
    width: 230px;
  }

  .sd-brand span {
    font-size: 9px;
    margin-left: 58px;
  }

  .sd-hero-copy {
    padding: 42px 22px;
  }

  .sd-load-grid,
  .sd-band-steps,
  .sd-loop-card {
    grid-template-columns: 1fr;
  }

  .sd-layer {
    grid-template-columns: 32px 34px 1fr;
  }

  .sd-layer p {
    grid-column: 3;
  }

  .sd-footer {
    padding: 26px 18px 18px;
  }
}

/* Reference-style Systems Biology hero */
.systems-disease-page {
  --sd-gold: #d7ad62;
}

.systems-disease-page .sd-nav {
  align-items: center;
  background: linear-gradient(180deg, #071017 0%, #03090e 100%);
  border-bottom: 2px solid rgba(18, 49, 56, 0.9);
  display: flex;
  gap: clamp(22px, 2.2vw, 34px);
  min-height: 122px;
  padding: 0 clamp(16px, 2.2vw, 30px);
  position: relative;
  z-index: 5;
}

.systems-disease-page .sd-brand {
  border-right: 0;
  display: inline-flex;
  flex: 0 0 auto;
  flex-direction: column;
  justify-content: center;
  min-height: 122px;
  min-width: clamp(305px, 28vw, 350px);
  padding-left: 0;
}

.systems-disease-page .sd-brand img {
  filter: brightness(0) invert(1) contrast(1.12);
  height: 82px;
  width: clamp(285px, 25vw, 325px);
}

.systems-disease-page .sd-brand span {
  color: rgba(255, 255, 255, 0.88);
  font-size: 12px;
  font-weight: 800;
  letter-spacing: 0.03em;
  line-height: 1;
  margin-left: 88px;
  margin-top: -13px;
}

.systems-disease-page .sd-menu {
  align-items: center;
  display: flex;
  flex: 1 1 auto;
  gap: clamp(22px, 2.9vw, 46px);
  justify-content: flex-start;
  min-width: 0;
}

.systems-disease-page .sd-menu a {
  align-items: center;
  border-right: 0;
  color: rgba(255, 255, 255, 0.9);
  display: inline-flex;
  flex-direction: row;
  font-size: clamp(11px, 1vw, 13px);
  font-weight: 900;
  gap: 8px;
  line-height: 1.25;
  max-width: 150px;
  padding: 0;
  text-align: center;
  text-shadow: 0 1px 8px rgba(0, 0, 0, 0.55);
  text-transform: uppercase;
}

.systems-disease-page .sd-menu a.active,
.systems-disease-page .sd-menu a:hover {
  color: #18d6cf;
}

.systems-disease-page .sd-menu i {
  color: currentColor;
  font-size: 10px;
  opacity: 0.72;
}

.systems-disease-page .sd-nav-cta {
  align-items: center;
  border: 2px solid rgba(19, 200, 196, 0.78);
  border-radius: 7px;
  color: #19ccc7;
  display: inline-flex;
  flex: 0 0 auto;
  font-size: 13px;
  font-weight: 900;
  gap: 10px;
  min-height: 48px;
  padding: 0 18px;
  text-decoration: none;
  text-transform: uppercase;
  white-space: nowrap;
}

.systems-disease-page .sd-nav-cta i {
  border: 1px solid rgba(24, 214, 207, 0.55);
  border-radius: 4px;
  font-size: 17px;
  height: 24px;
  line-height: 22px;
  text-align: center;
  width: 24px;
}

.systems-disease-page .sd-nav-cta:hover {
  background: rgba(24, 214, 207, 0.12);
  color: #fff;
}

.systems-disease-page .sd-hero {
  background:
    radial-gradient(circle at 73% 42%, rgba(25, 211, 205, 0.16), transparent 32%),
    linear-gradient(90deg, #071016 0%, #07151c 42%, #061820 62%, #031016 100%);
  border-bottom: 2px solid rgba(92, 77, 50, 0.42);
  display: grid;
  grid-template-columns: minmax(580px, 51%) minmax(0, 49%);
  min-height: 552px;
  overflow: hidden;
  padding: 0;
  position: relative;
}

.systems-disease-page .sd-hero-copy {
  display: flex;
  flex-direction: column;
  justify-content: flex-start;
  padding: 58px 20px 28px clamp(42px, 4.6vw, 74px);
  position: relative;
  z-index: 2;
}

.systems-disease-page .sd-eyebrow {
  color: #18d6cf;
  display: block;
  font-size: clamp(15px, 1.45vw, 20px);
  font-weight: 900;
  letter-spacing: 0.03em;
  margin-bottom: 22px;
  text-transform: uppercase;
}

.systems-disease-page .sd-hero-copy h1 {
  color: #f7f0e8;
  font-family: "Playfair Display", Georgia, serif;
  font-size: clamp(40px, 3.85vw, 54px);
  font-weight: 600;
  line-height: 1.12;
  text-shadow: 0 2px 0 rgba(255, 255, 255, 0.18), 0 8px 20px rgba(0, 0, 0, 0.78);
}

.systems-disease-page .sd-hero-copy h1 span {
  color: #16c8c4;
  text-shadow: 0 0 18px rgba(20, 211, 207, 0.26);
}

.systems-disease-page .sd-hero-rule {
  background: var(--sd-gold);
  height: 4px;
  margin: 24px 0;
  width: 72px;
}

.systems-disease-page .sd-hero-copy p {
  color: rgba(255, 255, 255, 0.92);
  font-size: clamp(16px, 1.32vw, 20px);
  font-weight: 600;
  line-height: 1.54;
  max-width: 760px;
}

.systems-disease-page .sd-hero-pillars {
  align-items: center;
  display: flex;
  flex-wrap: wrap;
  gap: 0;
  margin-top: 28px;
  max-width: 860px;
}

.systems-disease-page .sd-hero-pillars div {
  align-items: center;
  border-left: 1px solid rgba(255, 255, 255, 0.24);
  display: inline-flex;
  gap: 14px;
  min-height: 58px;
  padding: 0 22px;
  text-align: left;
}

.systems-disease-page .sd-hero-pillars div:first-child {
  border-left: 0;
  padding-left: 0;
}

.systems-disease-page .sd-hero-pillars i {
  color: #24c8c0;
  font-size: 39px;
}

.systems-disease-page .sd-hero-pillars strong {
  color: #fff;
  font-size: 17px;
  font-weight: 900;
  line-height: 1.25;
  text-transform: none;
}

.systems-disease-page .sd-hero-actions {
  align-items: center;
  display: flex;
  flex-wrap: wrap;
  gap: 18px;
  margin-top: 28px;
}

.systems-disease-page .sd-primary-btn,
.systems-disease-page .sd-secondary-btn {
  align-items: center;
  border-radius: 6px;
  display: inline-flex;
  font-size: 15px;
  font-weight: 900;
  gap: 12px;
  justify-content: center;
  min-height: 54px;
  padding: 0 28px;
  text-decoration: none;
  text-transform: uppercase;
}

.systems-disease-page .sd-primary-btn {
  background: linear-gradient(90deg, #24c4c2 0%, #43d5cf 100%);
  box-shadow: 0 0 0 1px rgba(122, 255, 249, 0.25) inset, 0 12px 28px rgba(22, 207, 201, 0.24);
  color: #fff;
  min-width: 360px;
}

.systems-disease-page .sd-primary-btn i {
  font-size: 21px;
}

.systems-disease-page .sd-secondary-btn {
  background: rgba(3, 12, 16, 0.45);
  border: 2px solid rgba(75, 207, 202, 0.72);
  color: #fff;
  min-width: 260px;
}

.systems-disease-page .sd-primary-btn:hover,
.systems-disease-page .sd-secondary-btn:hover {
  color: #fff;
  transform: translateY(-1px);
}

.systems-disease-page .sd-hero-art {
  align-items: center;
  display: flex;
  justify-content: center;
  min-height: 552px;
  overflow: hidden;
  position: relative;
}

.systems-disease-page .sd-hero-art img {
  filter: contrast(1.08) saturate(1.08) brightness(0.9);
  height: 100%;
  max-height: none;
  max-width: none;
  object-fit: cover;
  object-position: 51% 35%;
  opacity: 1;
  width: 100%;
  -webkit-mask-image: linear-gradient(90deg, transparent 0%, #000 10%, #000 100%);
  mask-image: linear-gradient(90deg, transparent 0%, #000 10%, #000 100%);
}

.systems-disease-page .sd-orbit {
  background: rgba(0, 23, 28, 0.58);
  border: 2px solid rgba(23, 204, 199, 0.82);
  box-shadow: 0 0 24px rgba(23, 204, 199, 0.18);
  color: #24c8c0;
  font-size: 43px;
  height: 88px;
  width: 88px;
}

.systems-disease-page .sd-orbit.orbit-a {
  left: 14%;
  top: 12%;
}

.systems-disease-page .sd-orbit.orbit-b {
  right: 10%;
  top: 12%;
}

.systems-disease-page .sd-orbit.orbit-c {
  left: 10%;
  top: 48%;
}

.systems-disease-page .sd-orbit.orbit-d {
  right: 9%;
  top: 48%;
}

@media (max-width: 1180px) {
  .systems-disease-page .sd-nav {
    flex-wrap: wrap;
    min-height: auto;
    padding-bottom: 18px;
    padding-top: 18px;
  }

  .systems-disease-page .sd-brand {
    min-height: auto;
    min-width: 270px;
  }

  .systems-disease-page .sd-brand img {
    height: 68px;
    width: 270px;
  }

  .systems-disease-page .sd-brand span {
    font-size: 10px;
    margin-left: 72px;
    margin-top: -11px;
  }

  .systems-disease-page .sd-menu {
    flex-basis: 100%;
    order: 3;
  }

  .systems-disease-page .sd-hero {
    grid-template-columns: minmax(430px, 50%) minmax(0, 50%);
  }

  .systems-disease-page .sd-hero-copy {
    padding-top: 44px;
  }
}

@media (max-width: 900px) {
  .systems-disease-page .sd-hero {
    grid-template-columns: 1fr;
  }

  .systems-disease-page .sd-hero-art {
    min-height: 420px;
  }
}

@media (max-width: 720px) {
  .systems-disease-page .sd-nav {
    justify-content: space-between;
    padding: 14px 16px;
  }

  .systems-disease-page .sd-menu {
    display: none;
  }

  .systems-disease-page .sd-brand {
    min-width: 0;
  }

  .systems-disease-page .sd-brand img {
    height: 54px;
    width: 218px;
  }

  .systems-disease-page .sd-brand span {
    font-size: 8px;
    margin-left: 58px;
    margin-top: -8px;
  }

  .systems-disease-page .sd-nav-cta {
    font-size: 0;
    min-height: 44px;
    padding: 0 12px;
  }

  .systems-disease-page .sd-hero-copy {
    padding: 42px 22px 28px;
  }

  .systems-disease-page .sd-hero-copy h1 {
    font-size: clamp(34px, 10vw, 42px);
  }

  .systems-disease-page .sd-hero-pillars {
    gap: 16px 0;
  }

  .systems-disease-page .sd-hero-pillars div {
    border-left: 0;
    flex: 1 1 50%;
    padding: 0 12px 0 0;
  }

  .systems-disease-page .sd-primary-btn,
  .systems-disease-page .sd-secondary-btn {
    min-width: 100%;
    width: 100%;
  }

  .systems-disease-page .sd-hero-art {
    min-height: 330px;
  }

  .systems-disease-page .sd-orbit {
    display: none;
  }
}

@media (max-width: 1180px) {
  .sd-values-strip {
    grid-template-columns: repeat(2, minmax(0, 1fr));
    width: calc(100% - 40px);
  }

  .sd-values-strip article {
    border-top: 1px solid rgba(8, 45, 54, 0.12);
    padding: 22px 24px;
  }

  .sd-values-strip article:nth-child(-n + 2) {
    border-top: 0;
  }

  .sd-values-strip article:nth-child(odd) {
    border-left: 0;
  }

  .sd-footer {
    padding-left: 28px;
    padding-right: 28px;
  }

  .sd-footer-main {
    grid-template-columns: repeat(2, minmax(0, 1fr));
  }

  .sd-footer-brand,
  .sd-footer-col,
  .sd-footer-connect {
    border-left: 0;
    padding-left: 0;
  }
}

@media (max-width: 720px) {
  .sd-values-strip {
    grid-template-columns: 1fr;
    padding: 0;
    width: calc(100% - 24px);
  }

  .sd-values-strip article,
  .sd-values-strip article:nth-child(-n + 2) {
    border-left: 0;
    border-top: 1px solid rgba(8, 45, 54, 0.12);
  }

  .sd-values-strip article:first-child {
    border-top: 0;
  }

  .sd-footer-main {
    grid-template-columns: 1fr;
  }

  .sd-footer-brand img {
    height: 58px;
    width: 240px;
  }

  .sd-footer-bottom {
    align-items: flex-start;
    flex-direction: column;
    gap: 10px;
  }
}

@media (max-width: 720px) {
  .systems-disease-page .sd-paper {
    overflow: hidden;
    padding-left: 12px;
    padding-right: 12px;
  }

  .systems-disease-page .sd-equation-card {
    grid-template-columns: 1fr;
    overflow: hidden;
    padding: 22px 16px;
  }

  .systems-disease-page .sd-equation-main {
    padding-left: 0;
  }

  .systems-disease-page .sd-formula {
    display: flex;
    flex-wrap: wrap;
    gap: 8px 10px;
    justify-content: center;
    padding-top: 18px;
  }

  .systems-disease-page .sd-formula strong {
    font-size: 15px;
    white-space: normal;
  }

  .systems-disease-page .sd-formula em {
    font-size: 16px;
  }

  .systems-disease-page .sd-formula-items {
    grid-template-columns: 1fr;
    gap: 12px;
    margin-top: 18px;
  }

  .systems-disease-page .sd-formula-items div,
  .systems-disease-page .sd-formula-items div:first-child {
    border-left: 0;
    border-top: 1px solid rgba(8, 45, 54, 0.13);
    padding: 16px 8px 0;
  }

  .systems-disease-page .sd-formula-items div:first-child {
    border-top: 0;
  }

  .systems-disease-page .sd-formula-items p {
    max-width: 100%;
  }
}